Cholangiocarcinoma Treatment Overview

Cholangiocarcinoma, commonly known as bile duct cancer, poses significant treatment challenges due to its advanced stage at diagnosis. Treatment options are influenced by tumor location, stage, and resectability.

Surgical Management

Surgery is the only potentially curative treatment, but most tumors are considered incurable. For those with resectable disease, surgical options include:

• Complete surgical removal of the tumor
• Partial hepatectomy
• Bile duct resection with lymphadenectomy

Systemic Therapy Options

Chemotherapy

The standard first-line treatment combines gemcitabine and cisplatin.

Immunotherapy

Agents like Durvalumab are now part of the treatment regimen.

Targeted Therapy

FGFR inhibitors are emerging as essential options.

Radiation Therapy

Radiation serves various roles, including adjuvant and palliative therapy.

Emerging Treatment Approaches

New trials are exploring combined therapies and genetic profiling for personalized treatment.

For more information and personalized guidance, consult with your healthcare provider.