Angiomyolipoma Treatment Options: Comprehensive Guide

Angiomyolipoma Treatment Options: Comprehensive Guide
Angiomyolipoma Treatment Options: Comprehensive Guide

Angiomyolipoma Treatment Options

Angiomyolipoma (AML) is a benign kidney tumor that may require treatment based on its size and symptoms. Multiple effective treatment options exist for managing this condition.

Surgical Management

Surgery is a common approach for angiomyolipomas, accounting for ~31% of treatments. Options include:

  • Nephron-Sparing Surgery (NSS): Preserves kidney function while removing the tumor.
  • Partial Nephrectomy: Removes only the tumor-containing part of the kidney.
  • Radical Nephrectomy: Complete removal of the kidney may be necessary for large tumors.

Embolization Therapy

Selective Angiographic Embolization is a minimally invasive option for managing bleeding and preventing complications. This technique blocks blood supply to the tumor.

Ablative Therapies

Methods like radiofrequency, thermal, and cryoablation can effectively destroy tumor tissue with less invasiveness.

Medical Therapy

For patients with tuberous sclerosis complex, mTOR inhibitors such as everolimus can reduce tumor size significantly.

Treatment Selection Factors

Choosing a treatment depends on tumor characteristics and patient health. Medical therapy is often favored to preserve kidney function.